Dyslipidemia

FDA Approves Pitavastatin for Mixed Dyslipidemia and Hyperlipidemia

FDA Approves Pitavastatin for Mixed Dyslipidemia and Hyperlipidemia

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The FDA has approved a new pitavastatin for the treatment of primary hyperlipidemia or mixed dyslipidemia.

Anacetrapib Reduces Major Coronary Events When Added to Intensive Statin Therapy

Anacetrapib Reduces Major Coronary Events When Added to Intensive Statin Therapy

Lower incidence of major coronary events for patients with atherosclerotic vascular disease receiving intensive statins is linked with use of anacetrapib.

Cardiovascular Event Risk Better Predicted by ApoB vs LDL Cholesterol Level

Cardiovascular Event Risk Better Predicted by ApoB vs LDL Cholesterol Level

Clinical benefit of reduced low-density lipoprotein cholesterol (LDL-C) levels may depend on the corresponding reduction in apolipoprotein B (apoB)-containing lipoprotein particles.

Anti-Tumor Necrosis Factor Drug Improves CV Health in Psoriatic Arthritis

Anti-Tumor Necrosis Factor Drug Improves CV Health in Psoriatic Arthritis

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Cardiovascular health in psoriatic arthritis improves with anti-tumor necrosis factor drug etanercept.

PCSK9 Inhibitor Evolocumab Continues to Lack Cost-Effectiveness

PCSK9 Inhibitor Evolocumab Continues to Lack Cost-Effectiveness

Findings for addition of evolocumab to standard tx in atherosclerotic cardiovascular disease

Antidepressant Mislabeled as Cholesterol Drug: Recall

Antidepressant Mislabeled as Cholesterol Drug: Recall

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International Laboratories, LLC has issued a recall for one lot of Pravastatin Sodium Tablets 40mg due to mislabeling.

Evolocumab Added to Statin Therapy Does Not Affect Cognition

Evolocumab Added to Statin Therapy Does Not Affect Cognition

There is no significant difference in cognitive function for patients treated with evolocumab or placebo added to statin therapy.

Marked Variations in Statin Use in Nursing Home Residents

Marked Variations in Statin Use in Nursing Home Residents

Statin prescribing trends vary among nursing home residents with significant variation of prescribing across physicians.

Multiple Cardiometabolic Comorbidities Prevalent in Psoriasis

Multiple Cardiometabolic Comorbidities Prevalent in Psoriasis

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Patients with psoriasis have high rates of cardiometabolic comorbidities.

Noncalcified, High-Risk Coronary Plaque Burden Increased With Psoriasis

Noncalcified, High-Risk Coronary Plaque Burden Increased With Psoriasis

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Individuals with psoriasis have a greater risk for noncalcified coronary plaque burden compared with healthy individuals and patients with hyperlipidemia.

FDA Approves Pitavastatin as Adjunctive Therapy for Hyperlipidemia or Mixed Dyslipidemia

FDA Approves Pitavastatin as Adjunctive Therapy for Hyperlipidemia or Mixed Dyslipidemia

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The FDA has approved Zypitamag for the treatment of patients with primary hyperlipidemia or mixed dyslipidemia.

Statins Reduce Cardiovascular Events, Death Even With Adverse Reactions

Statins Reduce Cardiovascular Events, Death Even With Adverse Reactions

Statin use after an adverse reaction is associated with lower incidences of cardiovascular events and death.

Glycemic Control Improves With Hepatitis C Treatment

Glycemic Control Improves With Hepatitis C Treatment

Direct-acting antiviral treatment for hepatitis C virus is linked to improved glycemic control in patients with type 2 diabetes.

CVD Risk in Juvenile Idiopathic Arthritis May Be Linked to Vitamin D Levels

CVD Risk in Juvenile Idiopathic Arthritis May Be Linked to Vitamin D Levels

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Serum Vitamin D levels are related to cholesterol levels and other risk factors for cardiovascular disease in patients with juvenile idiopathic arthritis.

PCSK9 Inhibitor Trends in Type 1 Diabetes

PCSK9 Inhibitor Trends in Type 1 Diabetes

PCSK9 had a significant correlation with hemoglobin A1c, triglycerides, total cholesterol, LDL cholesterol, and apolipoprotein B in patients with type 1 diabetes.

Total Cholesterol, Low-Density Lipoprotein Cholesterol Levels Affect Parkinson's Risk

Total Cholesterol, Low-Density Lipoprotein Cholesterol Levels Affect Parkinson's Risk

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A decreased risk in Parkinson's disease has been associated with total serum cholesterol and low-density lipoprotein cholesterol in men not on statin therapy.

Statins May Increase Risk for Mortality in Type 2 Diabetes

Statins May Increase Risk for Mortality in Type 2 Diabetes

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In a study,patients with type 2 diabetes presented better glycemic control and had higher risk for mortality when not taking statins.

Cholesterol Significantly Reduced by Blocking Angiopoietin-like 3 Gene

Cholesterol Significantly Reduced by Blocking Angiopoietin-like 3 Gene

Two research groups successfully reduced cholesterol in humans to block the angiopoietin-like 3 gene.

Refill Synchronization Beneficial for Medication Adherence

Refill Synchronization Beneficial for Medication Adherence

Appointment-based models improve medication-taking behavior.

Dapagliflozin May Benefit Progression of Atherosclerosis

Dapagliflozin May Benefit Progression of Atherosclerosis

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Dapagliflozin improved endothelial function in patients with type 2 diabetes.

Long-Term Outcomes of Evacetrapib on Cardiovascular Outcomes

Long-Term Outcomes of Evacetrapib on Cardiovascular Outcomes

Evacetrapib does not affect the primary efficacy end point of first occurrence of any component of a composite of death from cardiovascular causes in patients with high-risk vascular disease.

Targeted Approach Needed for Cholesterol Screenings

Targeted Approach Needed for Cholesterol Screenings

Study shows prevalence of atherosclerotic cardiovascular disease risk among adults under 50 without diabetes is low.

Are Patients Aware the Importance of Cholesterol Management?

Are Patients Aware the Importance of Cholesterol Management?

An American Heart Association survey found that patients felt least informed about the differences in cholesterol types and goals for cholesterol management.

Cognition Not Adversely Affected by Evolocumab With Statin Therapy

Cognition Not Adversely Affected by Evolocumab With Statin Therapy

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No differences were seen in measures of executive function between the evolocumab and placebo groups.

LDL-C Lowered Below Current Targets Beneficial to Atherosclerotic CVD

LDL-C Lowered Below Current Targets Beneficial to Atherosclerotic CVD

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Evolocumab reduced LDL-C levels by 59% and lowered the risk of CV death, MI, stroke, hospitalization for unstable angina, or coronary revascularization by 15%.

Bococizumab Reduced Cardiovascular Events in High-Risk But Not Low-Risk Patients

Bococizumab Reduced Cardiovascular Events in High-Risk But Not Low-Risk Patients

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In the combined SPIRE trials, the mean change in LDL-C levels was −56.0% in the bococizumab group and +2.9% in the placebo group.

On-Treatment Low-Density Lipoprotein Level Differences in Women vs Men

On-Treatment Low-Density Lipoprotein Level Differences in Women vs Men

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Women have lower rates of major adverse cardiovascular events despite having higher on-treatment low-density lipoprotein cholesterol levels than men.

Nocturnal, Daytime Hypoglycemia Effects on Arrhythmia Risk in Type 1 Diabetes

Nocturnal, Daytime Hypoglycemia Effects on Arrhythmia Risk in Type 1 Diabetes

Compared with matched euglycemia, bradycardia was more frequent during nocturnal hypoglycemia.

Early vs Delayed Statin Therapy in Acute Ischemic Stroke

Early vs Delayed Statin Therapy in Acute Ischemic Stroke

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Between the 2 statin groups, there were no significant changes in LDL-C or NIH Stroke Scale/Score.

Dyslipidemia and Atherosclerosis Clinical Practice Guidelines

Dyslipidemia and Atherosclerosis Clinical Practice Guidelines

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New guidelines for dyslipidemia management and atherosclerosis prevention include a wider range of disease stages and more aggressive intervention.

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