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Dyslipidemia and Atherosclerosis Clinical Practice Guidelines

Dyslipidemia and Atherosclerosis Clinical Practice Guidelines

New guidelines for dyslipidemia management and atherosclerosis prevention include a wider range of disease stages and more aggressive intervention.

Latest Features

PCSK9 Inhibitor Alirocumab Associated With 75% Reduction in Apheresis

PCSK9 Inhibitor Alirocumab Associated With 75% Reduction in Apheresis

Among patients with heterozygous familial hypercholesterolemia, alirocumab was associated with a 75% reduction in lipoprotein apheresis compared with placebo.

Statins Limit Vaccine Efficacy of Influenza Strain

Statins Limit Vaccine Efficacy of Influenza Strain

Statin use modified vaccine effectiveness and influenza risk for A(H3N2) infection but not for A(H1N1).

Higher Vitamin D Levels May Related to Higher Total Cholesterol, HDL-C

Higher Vitamin D Levels May Related to Higher Total Cholesterol, HDL-C

Vitamin D may influence cardiovascular disease risk via its effect on lipid levels.

Considering Cardiovascular Risks of Antidiabetic Drugs

Considering Cardiovascular Risks of Antidiabetic Drugs

A review of current antidiabetic drug treatments available and their individual cardiovascular risk profiles.

PCSK9 Inhibitors: Breakthrough in LDL-C Reduction, But Comes at a Cost

PCSK9 Inhibitors: Breakthrough in LDL-C Reduction, But Comes at a Cost

PCSK9 inhibitors may offer hope to patients with familial hypercholesterolemia who cannot tolerate or achieve goal LDL-C levels with statins.

LATEST NEWS

Are Patients Aware the Importance of Cholesterol Management?

Are Patients Aware the Importance of Cholesterol Management?

An American Heart Association survey found that patients felt least informed about the differences in cholesterol types and goals for cholesterol management.

Cognition Not Adversely Affected by Evolocumab With Statin Therapy

Cognition Not Adversely Affected by Evolocumab With Statin Therapy

No differences were seen in measures of executive function between the evolocumab and placebo groups.

LDL-C Lowered Below Current Targets Beneficial to Atherosclerotic CVD

LDL-C Lowered Below Current Targets Beneficial to Atherosclerotic CVD

Evolocumab reduced LDL-C levels by 59% and lowered the risk of CV death, MI, stroke, hospitalization for unstable angina, or coronary revascularization by 15%.

Bococizumab Reduced Cardiovascular Events in High-Risk But Not Low-Risk Patients

Bococizumab Reduced Cardiovascular Events in High-Risk But Not Low-Risk Patients

In the combined SPIRE trials, the mean change in LDL-C levels was −56.0% in the bococizumab group and +2.9% in the placebo group.

On-Treatment Low-Density Lipoprotein Level Differences in Women vs Men

On-Treatment Low-Density Lipoprotein Level Differences in Women vs Men

Women have lower rates of major adverse cardiovascular events despite having higher on-treatment low-density lipoprotein cholesterol levels than men.

Nocturnal, Daytime Hypoglycemia Effects on Arrhythmia Risk in Type 1 Diabetes

Nocturnal, Daytime Hypoglycemia Effects on Arrhythmia Risk in Type 1 Diabetes

Compared with matched euglycemia, bradycardia was more frequent during nocturnal hypoglycemia.

Early vs Delayed Statin Therapy in Acute Ischemic Stroke

Early vs Delayed Statin Therapy in Acute Ischemic Stroke

Between the 2 statin groups, there were no significant changes in LDL-C or NIH Stroke Scale/Score.

Dyslipidemia and Atherosclerosis Clinical Practice Guidelines

Dyslipidemia and Atherosclerosis Clinical Practice Guidelines

New guidelines for dyslipidemia management and atherosclerosis prevention include a wider range of disease stages and more aggressive intervention.

Can Vitamin D Improve Statin Efficacy in Patients With HIV?

Can Vitamin D Improve Statin Efficacy in Patients With HIV?

While patients taking rosuvastatin did not see an increase in 25(OH)D levels, baseline vitamin D deficiency decreased rouvastatin's effectiveness.

HbA1c Related to Aortic Stiffness, Even Without Diabetes

HbA1c Related to Aortic Stiffness, Even Without Diabetes

Glycated hemoglobin and homeostatic model assessment of insulin resistance correlated with progression of carotid femoral pulse wave velocity.

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