Coronary Artery Disease

Rivaroxaban Approved to Reduce Risk of Major Cardiovascular Events in CAD, PAD

Rivaroxaban Approved to Reduce Risk of Major Cardiovascular Events in CAD, PAD

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The FDA has approved Xarelto (rivaroxaban) to reduce the risk of MACE, such as CV death, myocardial infarction and stroke, in patients with chronic coronary or peripheral artery disease.

Triglyceride-Lowering Alleles Associated With Reduced Coronary Artery Disease Risk

Triglyceride-Lowering Alleles Associated With Reduced Coronary Artery Disease Risk

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Triglyceride-lowering variants in the lipoprotein lipase pathway are independently associated with protection from coronary artery disease and type 2 diabetes.

PCI, CABG Both Acceptable for LMCAD With Chronic Kidney Disease

PCI, CABG Both Acceptable for LMCAD With Chronic Kidney Disease

For patients with LMCAD, those with and without CKD, undergoing revascularization have similar long-term outcomes with PCI and CABG.

Addition of CT angiography to standard care for stable chest pain reduces mortality due to coronary disease

Patients with stable chest pain referred to a cardiology clinic who received standard care plus coronary CT angiography (CTA) experienced lower 5-year rate of death due to coronary disease compared to those receiving standard care alone.

Greater CAD Incidence, Heart Mass in Firefighter Cardiac Arrests

Greater CAD Incidence, Heart Mass in Firefighter Cardiac Arrests

Predictors of cardiac death included heart weight >450 g, coronary artery stenosis, and prior MI.

Ticagrelor Without Concomitant Aspirin No Better Than Standard DAPT in PCI

Ticagrelor Without Concomitant Aspirin No Better Than Standard DAPT in PCI

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Ticagrelor without aspirin offered no additional benefits compared with conventional dual antiplatelet therapy in patients undergoing PCI for either CAD or ACS.

Familial Hypercholesterolemia Benefits From Genetic Screening

Familial Hypercholesterolemia Benefits From Genetic Screening

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Genetic screening for familial hypercholesterolemia would improve the likelihood of a definitive diagnosis and may help clinicians choose the appropriate therapy for patients.

Relationship Between HbA1c and Coronary Artery Disease

Relationship Between HbA1c and Coronary Artery Disease

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Investigators examined the relationship between HbA1c with cardiovascular disease and it's subtypes.

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy

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A follow-up study from KEEPS found that cessation of menopausal hormone therapy did not change the expected trajectory of carotid artery intima-media thickness over a 3-year period.

Chronic Total Occlusions on CCTA Increase Major Adverse Cardiac Event Risk

Chronic Total Occlusions on CCTA Increase Major Adverse Cardiac Event Risk

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A significantly higher rate of adverse cardiac events was observed in chronic total occlusions compared with moderate to severe coronary artery disease.

SYNTAX Score II Predicts Mortality in 1- and 2-Vessel Disease

SYNTAX Score II Predicts Mortality in 1- and 2-Vessel Disease

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The SYNTAX score II was an independent predictor of mortality in patients with 1- and 2-vessel disease undergoing percutaneous coronary intervention.

Outcomes of Treatment Strategies in T2D, Stable CAD According to Angina Severity

Outcomes of Treatment Strategies in T2D, Stable CAD According to Angina Severity

Investigators demonstrated that angina severity at baseline should be a less important aspect of the diagnostic and therapeutic algorithm.

Carotid Intima Media Thickness Not Reduced With Levothyroxine in Subclinical Hypothyroidism

Carotid Intima Media Thickness Not Reduced With Levothyroxine in Subclinical Hypothyroidism

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Treatment with levothyroxine to normalize thyroid-stimulating hormone did not significantly reduce carotid intima media thickness in elderly patients with subclinical hypothyroidism.

Cardiovascular Comorbidity Tied to Hearing Loss in Older Old

Cardiovascular Comorbidity Tied to Hearing Loss in Older Old

Hearing loss is more strongly linked to cardiovascular disease risk factors in men vs women.

Personalized Goals, Cash Motivated Exercise in Ischemic Heart Disease

Personalized Goals, Cash Motivated Exercise in Ischemic Heart Disease

Loss-framed financial incentives with personalized goal setting helped increase daily step counts in patients with ischemic heart disease.

CAD Testing, Treatment Changes After Malpractice Damage Caps

CAD Testing, Treatment Changes After Malpractice Damage Caps

There was a decrease in invasive testing as first diagnostic test and fewer patients were referred for angiography after stress test.

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

Noninvasive CAD Screening May Reduce Cardiac Events in Individuals With Asymptomatic Diabetes

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Compared with standard care, noninvasive coronary artery disease screening reduced cardiac events by 27% in individuals with asymptomatic diabetes. Results justify larger, appropriately powered trials to potentially revisit current recommendations.

CABG May Have Better Outcomes Than PCI in Diabetes With LV Dysfunction

CABG May Have Better Outcomes Than PCI in Diabetes With LV Dysfunction

In patients with diabetes, multivessel coronary artery disease, and left ventricular dysfunction, coronary artery bypass grafting was associated with a reduction in major adverse cardiac and cerebrovascular events and mortality.

Coronary Artery Disease in Diabetes: Disease Extent Similar in Women, Men

Coronary Artery Disease in Diabetes: Disease Extent Similar in Women, Men

Both men and women with type 1 diabetes had similar extent of coronary artery disease when admitted for coronary angiography.

Safety, Effectiveness of Drug-Eluting Stents in Left Main CAD

Safety, Effectiveness of Drug-Eluting Stents in Left Main CAD

There were no significant differences for the observed 3-year rates of target vessel failure for different types of drug-eluting stents in patients with left main coronary artery disease.

CABG Offers Better Long-Term Outcomes in Younger Adults With CAD

CABG Offers Better Long-Term Outcomes in Younger Adults With CAD

Percutaneous coronary intervention is associated with increased rates of adverse outcomes compared with CABG in patients with 3-vessel CAD.

High-Risk Coronary Plaque Detection by CTA in Chest Pain May Predict MACE

High-Risk Coronary Plaque Detection by CTA in Chest Pain May Predict MACE

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Patients with stable chest pain who have high-risk plaque as identified by coronary computed tomographic angiography may have a higher risk for MACE.

PCI With Incomplete Revascularization in Certain Vessels May Increase Mortality Risk

PCI With Incomplete Revascularization in Certain Vessels May Increase Mortality Risk

The risk of mortality is increased for certain patients undergoing percutaneous coronary intervention with incomplete revascularization.

Wider Statin Use May Prevent More Atherosclerotic CVD Events

Wider Statin Use May Prevent More Atherosclerotic CVD Events

Guidelines that recommend statins for more people for primary prevention of atherosclerosis are likely to prevent more ASCVD events than guidelines that recommend fewer people take statins.

Mental Stress-Induced Myocardial Ischemia: Differences Between the Sexes

Mental Stress-Induced Myocardial Ischemia: Differences Between the Sexes

Cardiovascular reactivity mechanisms for mental stress-induced myocardial ischemia differ between sexes.

Cardiologists May Have Gender Bias When Treating Suspected CAD

Cardiologists May Have Gender Bias When Treating Suspected CAD

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Gender bias within cardiologists explains gender differences in clinical decision-making for suspected CAD.

Multivessel CAD With Diabetes: Choosing an Optimal Revascularization Strategy

Multivessel CAD With Diabetes: Choosing an Optimal Revascularization Strategy

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Patients with multivessel coronary artery disease and diabetes may benefit more from coronary artery bypass grafting surgery vs percutaneous coronary intervention.

Rivaroxaban Supplemental Drug Application Submitted to FDA for New Indications

Rivaroxaban Supplemental Drug Application Submitted to FDA for New Indications

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Two new indications for rivaroxaban submitted to the FDA to reduce the risk of major cardiovascular events in patients with chronic CAD and/or PAD.

Necessity of PCI in Stable Coronary Artery Disease Questioned

Necessity of PCI in Stable Coronary Artery Disease Questioned

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No evidence shows efficacy of PCI procedures for patients with stable coronary artery disease with angina.

Exercise Time After Percutaneous Coronary Intervention for Angina

Exercise Time After Percutaneous Coronary Intervention for Angina

Percutaneous coronary intervention does not increase exercise time more than a placebo procedure in patients with angina and severe coronary stenosis.

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