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FOURIER Trial Data Questions: Are PCSK9 Inhibitors The Right Choice?

FOURIER Trial Data Questions: Are PCSK9 Inhibitors The Right Choice?

Results of the FOURIER trial, presented at the 2017 ACC Scientific Sessions, raise questions about the efficacy of PCSK9 inhibitors as long-term therapy for patients with atherosclerotic CVD.

Latest Features

Identifying At-Risk Patients Using Coronary Artery Calcium Scores

Identifying At-Risk Patients Using Coronary Artery Calcium Scores

Researchers argue that elevated coronary artery calcium scores increase the risk of adverse cardiovascular events even in young patients.

Oxygen Therapy for Acute MI: Best Practice or Harmful Treatment?

Oxygen Therapy for Acute MI: Best Practice or Harmful Treatment?

Evidence is lacking to support oxygen therapy for acute myocardial infarction.

Coronary Heart Disease in HIV/AIDS: Confronting 2 Major Health Issues

Coronary Heart Disease in HIV/AIDS: Confronting 2 Major Health Issues

A review of cardiovascular disease burden, particularly coronary heart disease, in HIV/AIDS.

Reducing the Progression of Coronary Heart Disease With Estradiol

Reducing the Progression of Coronary Heart Disease With Estradiol

In light of ELITE trial results, estradiol hormone therapy may have a role in coronary heart disease treatment.

PCSK9 Inhibitors: Breakthrough in LDL-C Reduction, But Comes at a Cost

PCSK9 Inhibitors: Breakthrough in LDL-C Reduction, But Comes at a Cost

PCSK9 inhibitors may offer hope to patients with familial hypercholesterolemia who cannot tolerate or achieve goal LDL-C levels with statins.

Latest News

Is Pravastatin Effective as Primary Prevention Against CHD Events in Elderly?

Is Pravastatin Effective as Primary Prevention Against CHD Events in Elderly?

No differences were observed between pravastatin and usual care for CHD events, cause-specific deaths, stroke, cancer, and combination fatal CHD or nonfatal MI.

Impaired Coronary Distensibility Index Linked to Adverse Childhood Experience, Increases MACE Risk

Impaired Coronary Distensibility Index Linked to Adverse Childhood Experience, Increases MACE Risk

Individuals with adverse childhood experience may be at greater risk for major adverse cardiovascular events.

Gluten Does Not Increase Coronary Heart Disease Risk in General Population

Gluten Does Not Increase Coronary Heart Disease Risk in General Population

A gluten-free diet is not recommended for individuals without celiac disease to prevent coronary heart disease.

Measuring Visceral Adipose Tissue With DXA to Predict Atherosclerotic CVD

Measuring Visceral Adipose Tissue With DXA to Predict Atherosclerotic CVD

Fourteen percent of study participants experienced incident athersclerotic cardiovascular disease events.

Gray Hair Predictive of Coronary Artery Disease in Men

Gray Hair Predictive of Coronary Artery Disease in Men

Hair whitening score, hypertension, and dyslipidemia were all independent predictors of atherosclerotic coronary artery disease.

CVD Risk Predicted By Fasting Pancreatic Polypeptide in Type 2 Diabetes

CVD Risk Predicted By Fasting Pancreatic Polypeptide in Type 2 Diabetes

Fasting pancreatic polypeptide may be a marker for macrovascular disease.

Recurrent MI Risk, CHD Events Increased with Statin Intolerance

Recurrent MI Risk, CHD Events Increased with Statin Intolerance

Patients with statin intolerance had a 36% higher rate of recurrent myocardial infarction compared with patients with high statin adherence.

ACC Updated Criteria: Coronary Revascularization in Stable Ischemic Heart Disease

ACC Updated Criteria: Coronary Revascularization in Stable Ischemic Heart Disease

Revised coronary revascularization criteria rated whether coronary interventions are appropriate in tables organized according to practice patterns.

Increased Cardiovascular Disease Risk With Darunavir Therapy

Increased Cardiovascular Disease Risk With Darunavir Therapy

Risk of cardiovascular disease gradually increased in patients undergoing darunavir therapy.

Multi-Protein Blood Test Sensitive, Effective in Coronary Artery Disease Screening

Multi-Protein Blood Test Sensitive, Effective in Coronary Artery Disease Screening

The HART test has been found to be more accurate than standard diagnostic methods in identifying coronary artery disease.

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