Atrial Fibrillation

Apixaban Is Safest Direct Oral Anticoagulant vs Warfarin

Apixaban Is Safest Direct Oral Anticoagulant vs Warfarin

Apixaban reduced risks of major, intracranial, and gastrointestinal bleeding compared with warfarin.

Weight Loss Linked to Reversal of Atrial Fibrillation Progression

Weight Loss Linked to Reversal of Atrial Fibrillation Progression

Increased weight loss with risk factor management associated with greater atrial fibrillation freedom.

Variation in Quality of Trials for Atrial Fibrillation, Flutter

Variation in Quality of Trials for Atrial Fibrillation, Flutter

Most common trial end point is atrial fibrillation or atrial flutter recurrence; rates of primary clinical end points are low.

Atrial Fibrillation Risk Linked to Sleep Disruption

Atrial Fibrillation Risk Linked to Sleep Disruption

Higher risk for atrial fibrillation seen across multiple cohorts, regardless of obstructive sleep apnea and other possible factors.

Troponin-T, NT-proBNP May Predict Mortality Risk in Atrial Fibrillation

Troponin-T, NT-proBNP May Predict Mortality Risk in Atrial Fibrillation

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Troponin-T, N-terminal pro-B-type natriuretic peptide, and growth differentiation factor-15 may offer prognostic utility on mortality and bleeding events in patients with atrial fibrillation who receive anticoagulation.

Rivaroxaban Use in Older Patients: Does Age Influence Safety, Efficacy?

Rivaroxaban Use in Older Patients: Does Age Influence Safety, Efficacy?

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Data from large Phase 3 studies showed that treatment with rivaroxaban was found to be safe and effective in older patients.

Work Stress May Increase Risk of Developing Atrial Fibrillation

Work Stress May Increase Risk of Developing Atrial Fibrillation

Job strain linked with increased risk for incident atrial fibrillation.

New Coagulation Monitoring Device Allows for Wireless Reporting of INR Results

New Coagulation Monitoring Device Allows for Wireless Reporting of INR Results

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The system is intended for properly selected trained users ≥22 years of age who have been stabilized on anticoagulation with vitamin K antagonists for ≥6 weeks.

Stroke Risk Highest in Paroxysmal Afib With Greater Burden of Afib

Stroke Risk Highest in Paroxysmal Afib With Greater Burden of Afib

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A greater burden of atrial fibrillation or flutter in patients with paroxysmal atrial fibrillation was associated with a higher risk for stroke when not taking anticoagulants.

COPD May Increase the Risk for Atrial Fibrillation

COPD May Increase the Risk for Atrial Fibrillation

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Patients with COPD had a nearly 2-fold increased risk for developing atrial fibrillation compared with patients without COPD.

Vasopressin plus catecholamines lowers risk of atrial fibrillation in distributive shock

In this meta-analysis, addition of vasopressin to catecholamine vasopressors was associated with a lower risk for atrial fibrillation compared with catecholamine monotherapy. However, while there was decreased mortality with vasopressin plus catecholamines, this difference was not seen when restricting analysis to studies with a low risk for bias.

Long-Term Cardiovascular Risk for Endometrial Cancer Survivors

Long-Term Cardiovascular Risk for Endometrial Cancer Survivors

Endometrial cancer survivors have an elevated risk of various adverse long-term cardiovascular outcomes.

Andexxa Approved for Reversing Anticoagulant Activity of Rivaroxaban, Apixaban

Andexxa Approved for Reversing Anticoagulant Activity of Rivaroxaban, Apixaban

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Andexxa, a recombinant modified human Factor Xa (FXa) protein, was approved under the FDA's Accelerated Approval pathway.

Afib Risk Not Affected by Borderline ABI in Peripheral Artery Disease

Afib Risk Not Affected by Borderline ABI in Peripheral Artery Disease

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Peripheral artery disease with a borderline ankle-branchial index appears not to increase the risk for atrial fibrillation.

Anxiety May Increase Stroke, Intracranial Hemorrhage in Atrial Fibrillation

Anxiety May Increase Stroke, Intracranial Hemorrhage in Atrial Fibrillation

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Anxiety may increase the risk for ischemic stroke and intracranial hemorrhage in patients with atrial fibrillation.

Caffeine Does Not Appear to Be Linked to Risk for Arrhythmia

Caffeine Does Not Appear to Be Linked to Risk for Arrhythmia

Regular intake of coffee and tea seems safe and may be beneficial, although energy drinks may increase risk for arrhythmia.

Nut Consumption Associated With Reduced Risk for Atrial Fibrillation

Nut Consumption Associated With Reduced Risk for Atrial Fibrillation

Possible correlation also seen for nut consumption with reduced risk for heart failure, myocardial infarction, and abdominal aortic aneurysm.

Praxbind Gains Full FDA Approval as Pradaxa Reversal Agent

Praxbind Gains Full FDA Approval as Pradaxa Reversal Agent

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Complete reversal was seen within 4 hours in the majority of patients, as measured by ecarin clotting time (ECT 82%) or diluted thrombin time (dTT 99%). In addition, there was a low late of thrombotic events and no new safety events were reported.

Pulmonary Arterial Hypertension Outcomes With Atrial Arrhythmia

Pulmonary Arterial Hypertension Outcomes With Atrial Arrhythmia

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Increased right atrial and pulmonary wedge pressures and increased thyroid disease prevalence were associated with atrial arrhythmia development in idiopathic or systemic sclerosis-related pulmonary arterial hypertension.

Lower Thromboembolic Risk With New Afib After CABG vs NVAF

Lower Thromboembolic Risk With New Afib After CABG vs NVAF

For patients post coronary artery bypass graft surgery, new-onset postoperative atrial fibrillation is associated with lower long-term thromboembolic risk than that seen among patients with nonvalvular atrial fibrillation.

NSAID Use Linked to Afib Risk in Middle-Aged Asian Population

NSAID Use Linked to Afib Risk in Middle-Aged Asian Population

Risk up with use of non-selective NSAIDs and combined use of selective, non-selective NSAIDs.

Depression, Antidepressant Use May Up Risk of Atrial Fibrillation

Depression, Antidepressant Use May Up Risk of Atrial Fibrillation

Depression and use of an antidepressant are associated with atrial fibrillation.

Atrial Fibrillation Mortality May Increase With Digoxin

Atrial Fibrillation Mortality May Increase With Digoxin

Compared with patients not taking digoxin, patients with a serum digoxin concentration of ≥1.2 ng/mL had a 56% increased hazard of mortality.

Influenza Vaccination May Reduce Mortality Risk in Heart Failure

Influenza Vaccination May Reduce Mortality Risk in Heart Failure

A meta-analysis sought to determine the effect of influenza vaccination on cardiac-related mortality in patients with heart failure.

Ischemic Stroke Risk in Atrial Fibrillation Varies by Race

Ischemic Stroke Risk in Atrial Fibrillation Varies by Race

African-Americans are at an increased risk of developing an ischemic stroke before or after atrial fibrillation diagnosis compared with whites.

Digital Adherence Devices: Preventing Strokes in Afib One Reminder at a Time

Digital Adherence Devices: Preventing Strokes in Afib One Reminder at a Time

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Using digital adherence devices to improve medication adherence in patients with atrial fibrillation may reduce the rate of ischemic strokes.

Anticoagulants in Elderly With Afib, CKD May Increase Stroke Risk

Anticoagulants in Elderly With Afib, CKD May Increase Stroke Risk

Anticoagulants are associated with increased risk for ischemic stroke and hemorrhage in older patients with chronic kidney disease and a new diagnosis of atrial fibrillation.

Catheter ablation of atrial fibrillation in heart failure reduces mortality and hospitalization: The CASTLE-AF trial

Compared with medical therapy alone, catheter ablation of atrial fibrillation in patients with heart failure reduced the risk for all-cause mortality and hospitalization.

Targeting Underlying Conditions May Improve Sinus Rhythm in Atrial Fibrillation

Targeting Underlying Conditions May Improve Sinus Rhythm in Atrial Fibrillation

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Patients with persistent atrial fibrillation who received targeted therapy saw improvements in sinus rhythm as well as reductions in blood pressure, cholesterol, and weight.

A 45-Year-Old Man Presents to the ED With Shortness of Breath, Confusion

A 45-Year-Old Man Presents to the ED With Shortness of Breath, Confusion

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A 45-year-old man presents to the emergency department with some mental confusion and near syncope.

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