Atherosclerosis

Measuring Visceral Adipose Tissue With DXA to Predict Atherosclerotic CVD

Measuring Visceral Adipose Tissue With DXA to Predict Atherosclerotic CVD

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Fourteen percent of study participants experienced incident athersclerotic cardiovascular disease events.

Gray Hair Predictive of Coronary Artery Disease in Men

Gray Hair Predictive of Coronary Artery Disease in Men

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Hair whitening score, hypertension, and dyslipidemia were all independent predictors of atherosclerotic coronary artery disease.

FOURIER Trial Data Questions: Are PCSK9 Inhibitors The Right Choice?

FOURIER Trial Data Questions: Are PCSK9 Inhibitors The Right Choice?

Results of the FOURIER trial, presented at the 2017 ACC Scientific Sessions, raise questions about the efficacy of PCSK9 inhibitors as long-term therapy for patients with atherosclerotic CVD.

Patient-Clinician Communication Key in Managing Heart Disease Treatment

Patient-Clinician Communication Key in Managing Heart Disease Treatment

Two studies examined the positive outcomes of clear patient-clinician communication on management and treatment of heart disease.

Novel Multimodality Testing Strategy Improves CVD Risk Assessment

Novel Multimodality Testing Strategy Improves CVD Risk Assessment

A mutlimodal strategy combines 5 separate tests to significantly improve CVD and ASVCD risk assessment.

Statin Eligibility Requirements In African Americans With Atherosclerosis

Statin Eligibility Requirements In African Americans With Atherosclerosis

According to ACC/AHA Guidelines presented at ACC 2017, targeted imaging should be used to personalize statin recommendation programs.

LDL-C Lowered Below Current Targets Beneficial to Atherosclerotic CVD

LDL-C Lowered Below Current Targets Beneficial to Atherosclerotic CVD

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Evolocumab reduced LDL-C levels by 59% and lowered the risk of CV death, MI, stroke, hospitalization for unstable angina, or coronary revascularization by 15%.

Hormone Replacement Therapy Associated With Lower Coronary Artery Calcium Scores

Hormone Replacement Therapy Associated With Lower Coronary Artery Calcium Scores

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Hormone replacement therapy in postmenopausal women was associated with lower coronary artery calcium scores as well as lower risk of long-term all-cause mortality.

Oxidized Lipoprotein Biomarker Levels Affected by Age, Ethnicity

Oxidized Lipoprotein Biomarker Levels Affected by Age, Ethnicity

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Elevated IgG MDA-LDL levels are associated with a higher risk of subclinical atherosclerosis and may serve as accurate predictors of MACE

Increased Cardiovascular Disease Risk With Darunavir Therapy

Increased Cardiovascular Disease Risk With Darunavir Therapy

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Risk of cardiovascular disease gradually increased in patients undergoing darunavir therapy.

Care Setting Impacts Carotid Artery Stenosis Management

Care Setting Impacts Carotid Artery Stenosis Management

Patients were more likely to undergo procedural management in a fee-for-service system vs a salary-based system.

Amygdalar Activity Independently Predicts Cardiovascular Events

Amygdalar Activity Independently Predicts Cardiovascular Events

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Chronic stress identified as risk factor for cardiovascular disease.

CVD, Atherosclerosis Risk in Systemic Lupus Erythematosus

CVD, Atherosclerosis Risk in Systemic Lupus Erythematosus

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Patients with systemic lupus erythematosus had a net progression of mean carotid intima-media thickness, with or without depression.

Coronary Heart Disease in HIV/AIDS: Confronting 2 Major Health Issues

Coronary Heart Disease in HIV/AIDS: Confronting 2 Major Health Issues

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A review of cardiovascular disease burden, particularly coronary heart disease, in HIV/AIDS.

Coronary Atherosclerosis Prevalence in Psoriatic Arthritis

Coronary Atherosclerosis Prevalence in Psoriatic Arthritis

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A large number of patients with psoriatic arthritis may have silent coronary artery disease.

PCSK9 Synthesis Inhibitor Shows Promise in Lowering LDL-C

PCSK9 Synthesis Inhibitor Shows Promise in Lowering LDL-C

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A mean 51% reduction in low-density lipoprotein cholesterol was seen in the group assigned to the 300 mg dose of inclisiran.

Deferred vs Complete Revascularization in Patients With Diabetes

Deferred vs Complete Revascularization in Patients With Diabetes

Deferred revascularization in patients with diabetes, especially those with previous myocardial infarction, is associated with poor medium-term outcomes.

Cardiometabolic Syndrome Increases Risk of Subclinical Atherosclerosis

Cardiometabolic Syndrome Increases Risk of Subclinical Atherosclerosis

Participants with cardiometabolic syndrome had higher odds ratios of having a positive coronary artery calcification and carotid artery intima-media thickness.

High-Sensitivity Cardiac Troponin T Levels Linked to Cerebral Microbleeds

High-Sensitivity Cardiac Troponin T Levels Linked to Cerebral Microbleeds

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Patients in the highest hs-cTnT tertile were more likely to have cerebral microbleeds and deep or infratentorial cerebral microbleeds, after adjustments.

CVD Risk Management in Rheumatoid Arthritis: Updated Guidelines

CVD Risk Management in Rheumatoid Arthritis: Updated Guidelines

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The European League Against Rheumatism (EULAR) has released updated guidelines for cardiovascular disease risk assessment in patients with rheumatoid arthritis.

Current Smoking Linked to Changes in Cardiac Structure and Function

Current Smoking Linked to Changes in Cardiac Structure and Function

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Cumulative cigarette exposure correlated with increased measures of left ventricular mass and worse diastolic function.

Low Diastolic Blood Pressure Associated With Subclinical Myocardial Damage

Low Diastolic Blood Pressure Associated With Subclinical Myocardial Damage

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Low diastolic blood pressure may harm the myocardium, which could lead to coronary heart disease.

Psoriasis Associated With Increased Coronary Artery Calcium

Psoriasis Associated With Increased Coronary Artery Calcium

Similar to patients with diabetes, patients with psoriasis had low CV risk on the Framingham Risk Score, but high prevalence of CV and cardiometabolic risk factors.

Statin Limitation Could Benefit Elderly Patients

Statin Limitation Could Benefit Elderly Patients

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Specificity, or less overtreatment, increased from 15% to 25% for both coronary heart disease and cardiovascular disease

PCSK9 Inhibitors Not Cost-Effective in ASCVD

PCSK9 Inhibitors Not Cost-Effective in ASCVD

For PCSK9 inhibitors to be cost-effective at less than $100 000 per quality-adjusted life year, annual drug costs would need to be reduced to $4536 per patient or less.

Percutaneous Transluminal Renal Angioplasty vs Medical Therapy in Renal Artery Stenosis

Percutaneous Transluminal Renal Angioplasty vs Medical Therapy in Renal Artery Stenosis

Little benefit seen using percutaneous transluminal renal angioplasty with stent placement for patients with atherosclerotic renal artery stenosis.

Younger Patients With Familial Hypercholesterolemia May Have Greatest Risk for CHD and ASCVD

Younger Patients With Familial Hypercholesterolemia May Have Greatest Risk for CHD and ASCVD

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An up to 5-fold increased risk of coronary heart disease hazards was observed in the familial hypercholesterolemia phenotype group for ages 20 to 29.

Reducing the Progression of Coronary Heart Disease With Estradiol

Reducing the Progression of Coronary Heart Disease With Estradiol

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In light of ELITE trial results, estradiol hormone therapy may have a role in coronary heart disease treatment.

Subclinical Atherosclerosis Not Predicted by Average Leucocyte Telomere Length or Short Telomere Load

Subclinical Atherosclerosis Not Predicted by Average Leucocyte Telomere Length or Short Telomere Load

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Researchers studied associations between telomeres and atherosclerosis burden in femoral and carotid arteries in 3 regression models.

Cholesterol Efflux Capacity Improves Atherosclerotic CVD Risk Prediction

Cholesterol Efflux Capacity Improves Atherosclerotic CVD Risk Prediction

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Cholesterol efflux capacity remained inversely associated with incident atherosclerotic cardiovascular disease without attenuation in an adjusted model.

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